4DMT operates as a clinical-stage genetic medicines company focused on inventing and developing genetic medicines to treat large market diseases in ophthalmology, pulmonology and cardiology. It develops genetic medicines using its proprietary invention platform, Therapeutic Vector Evolution. It combines the power of the Nobel Prize-winning technology, directed evolution, with approximately one billion synthetic AAV capsid-derived sequences. Its product design, development and manufacturing engine create a valuable and diverse product pipeline. The company is currently advancing five clinical-stage and two preclinical product candidates, each tailored to address rare and large market diseases. 4DMT was founded by David H. Kirn, Melissa Kotterman, Theresa Janke, and David Schaffer on September 12, 2013 and is headquartered in Emeryville, CA.
| Insider Trading | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|
| Bizily Scott | Chief Legal Officer | Aug 13 '26 | Option Exercise | 4.14 | 1,635 | 6,769 | 10,252 | Aug 17 05:34 PM |
| Bizily Scott | Chief Legal Officer | Aug 17 '26 | Option Exercise | 4.14 | 1,635 | 6,769 | 10,252 | Aug 17 05:34 PM |
| Bizily Scott | Chief Legal Officer | Aug 17 '26 | Sale | 12.20 | 1,635 | 19,947 | 8,617 | Aug 17 05:34 PM |
| Bizily Scott | Chief Legal Officer | Aug 13 '26 | Sale | 12.00 | 1,635 | 19,620 | 8,617 | Aug 17 05:34 PM |
| SCOTT BIZILY | Officer | Aug 17 '26 | Proposed Sale | 12.19 | 6,540 | 79,723 | Aug 17 04:46 PM | |
| SCOTT BIZILY | Officer | Aug 13 '26 | Proposed Sale | 11.87 | 1,635 | 19,407 | Aug 13 04:33 PM | |
| Kirn David | See Remarks | Aug 04 '26 | Sale | 10.23 | 26,842 | 274,596 | 844,895 | Aug 05 04:10 PM |
| David Kirn | Officer | Aug 04 '26 | Proposed Sale | 10.26 | 26,842 | 275,399 | Aug 04 06:08 PM | |
| Kirn David | See Remarks | Aug 03 '26 | Sale | 10.05 | 12,415 | 124,722 | 871,737 | Aug 04 04:45 PM |
| David Kirn | Officer | Aug 03 '26 | Proposed Sale | 10.09 | 12,415 | 125,267 | Aug 03 05:29 PM | |
| Kirn David | See Remarks | Jul 09 '26 | Sale | 12.87 | 42,608 | 548,177 | 899,877 | Jul 14 05:04 PM |
| Kirn David | See Remarks | Jul 10 '26 | Sale | 12.03 | 15,725 | 189,233 | 884,152 | Jul 14 05:04 PM |
| David Kirn | Officer | Jul 10 '26 | Proposed Sale | 12.31 | 15,725 | 193,575 | Jul 10 04:54 PM | |
| David Kirn | Officer | Jul 09 '26 | Proposed Sale | 12.89 | 42,608 | 549,217 | Jul 09 05:21 PM | |
| SCOTT BIZILY | Officer | Jun 30 '26 | Proposed Sale | 12.88 | 6,566 | 84,570 | Jun 30 04:38 PM | |
| Bizily Scott | Chief Legal Officer | Jun 23 '26 | Option Exercise | 4.14 | 9,810 | 40,613 | 18,427 | Jun 25 04:38 PM |
| Bizily Scott | Chief Legal Officer | Jun 23 '26 | Sale | 12.00 | 9,810 | 117,720 | 8,617 | Jun 25 04:38 PM |
| SCOTT BIZILY | Officer | Jun 23 '26 | Proposed Sale | 10.42 | 9,810 | 102,220 | Jun 23 04:29 PM | |
| Kirn David | See Remarks | Jun 22 '26 | Sale | 10.47 | 114,746 | 1,200,851 | 942,485 | Jun 23 04:19 PM |
| David Kirn | Officer | Jun 22 '26 | Proposed Sale | 10.42 | 114,746 | 1,195,653 | Jun 22 05:58 PM | |
| Kirn David | See Remarks | Jun 01 '26 | Sale | 10.02 | 1,922 | 19,258 | 1,057,231 | Jun 02 04:48 PM |
| David Kirn | Officer | Jun 01 '26 | Proposed Sale | 9.71 | 1,922 | 18,663 | Jun 01 05:40 PM | |
| Gupta Ashoo | VP, Finance and Controller | Mar 20 '26 | Sale | 8.61 | 390 | 3,358 | 46,914 | Mar 24 06:30 PM |
| Gupta Ashoo | VP, Finance and Controller | Dec 20 '25 | Sale | 8.68 | 389 | 3,377 | 46,218 | Dec 23 09:05 PM |
| Bizily Scott | Chief Legal Officer | Dec 16 '25 | Option Exercise | 4.14 | 1,635 | 6,769 | 5,229 | Dec 19 04:10 PM |
| Bizily Scott | Chief Legal Officer | Dec 16 '25 | Sale | 10.90 | 1,635 | 17,822 | 3,594 | Dec 19 04:10 PM |
| THEUER CHARLES | Director | Dec 12 '25 | Option Exercise | 1.14 | 9,333 | 10,640 | 41,684 | Dec 16 04:35 PM |
| SCOTT BIZILY | Officer | Dec 16 '25 | Proposed Sale | 10.95 | 1,635 | 17,903 | Dec 16 04:33 PM | |
| Bizily Scott | Chief Legal Officer | Nov 17 '25 | Option Exercise | 4.14 | 1,635 | 6,769 | 5,229 | Nov 19 09:53 PM |
| Bizily Scott | Chief Legal Officer | Nov 17 '25 | Sale | 10.59 | 1,635 | 17,315 | 3,594 | Nov 19 09:53 PM |
| SCOTT BIZILY | Officer | Nov 17 '25 | Proposed Sale | 10.79 | 1,635 | 17,642 | Nov 17 04:33 PM | |
| Bizily Scott | Chief Legal Officer | Oct 24 '25 | Option Exercise | 6.49 | 1,084 | 7,035 | 6,272 | Oct 27 06:19 PM |
| Bizily Scott | Chief Legal Officer | Oct 24 '25 | Sale | 12.00 | 2,678 | 32,136 | 3,594 | Oct 27 06:19 PM |
| SCOTT BIZILY | Officer | Oct 24 '25 | Proposed Sale | 10.00 | 1,816 | 18,160 | Oct 24 04:26 PM | |
| Bizily Scott | Chief Legal Officer | Oct 16 '25 | Option Exercise | 4.14 | 1,635 | 6,769 | 6,823 | Oct 20 07:51 PM |
| Bizily Scott | Chief Legal Officer | Oct 16 '25 | Sale | 10.17 | 1,635 | 16,628 | 5,188 | Oct 20 07:51 PM |
| Bizily Scott | Chief Legal Officer | Oct 09 '25 | Sale | 10.00 | 2,408 | 24,080 | 5,188 | Oct 14 04:04 PM |
| Bizily Scott | Chief Legal Officer | Sep 23 '25 | Sale | 8.00 | 2,407 | 19,256 | 7,596 | Sep 26 09:50 PM |
| SCOTT BIZILY | Officer | Sep 23 '25 | Proposed Sale | 7.40 | 7,312 | 54,109 | Sep 23 04:20 PM |